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PAC11 dynein intermediate chain [ Saccharomyces cerevisiae S288C ]

Gene ID: 852099, updated on 8-Oct-2017
Gene symbol
PAC11
Gene description
dynein intermediate chain
Primary source
SGD:S000002896
Locus tag
YDR488C
Gene type
protein coding
RNA name
dynein intermediate chain
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See PAC11 in Map Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1429188..1430789, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Vps60p Neighboring gene 3,4-dihydroxy-2-butanone-4-phosphate synthase RIB3 Neighboring gene DNA replication protein SLD5 Neighboring gene serine/threonine protein kinase PKH1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Phagosome, organism-specific biosystem (from KEGG)
    Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Phagosome, conserved biosystem (from KEGG)
    Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to ATP-dependent microtubule motor activity, plus-end-directed IGI
Inferred from Genetic Interaction
more info
PubMed 
contributes_to ATP-dependent microtubule motor activity, plus-end-directed IMP
Inferred from Mutant Phenotype
more info
PubMed 
dynein heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
 
dynein light chain binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic dynein complex IPI
Inferred from Physical Interaction
more info
PubMed 
cytoplasmic dynein complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cytoplasmic microtubule IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
Names
dynein intermediate chain
NP_010776.1
  • Dynein intermediate chain, microtubule motor protein; required for intracellular transport and cell division; acts in cytoplasmic dynein pathway; forms complex with dynein light chain Dyn2p that promotes Dyn1p homodimerization and potentiates motor processivity; Dyn2p-Pac11p complex is also important for interaction of dynein motor complex with dynactin complex; forms cortical cytoplasmic microtubule capture site with Num1p; essential in the absence of CIN8

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1429188..1430789 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180796.1NP_010776.1  TPA: dynein intermediate chain [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010776.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P40960
    Conserved Domains (2) summary
    COG2319
    Location:385473
    WD40; WD40 repeat [General function prediction only]
    pfam00400
    Location:431466
    WD40; WD domain, G-beta repeat
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