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RIB3 3,4-dihydroxy-2-butanone-4-phosphate synthase RIB3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852098, updated on 4-Feb-2024

Summary

Gene symbol
RIB3
Gene description
3,4-dihydroxy-2-butanone-4-phosphate synthase RIB3
Primary source
SGD:S000002895
Locus tag
YDR487C
See related
AllianceGenome:SGD:S000002895
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables 3,4-dihydroxy-2-butanone-4-phosphate synthase activity. Involved in aerobic respiration and riboflavin biosynthetic process. Located in cytosol and mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See RIB3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1428354..1428980, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Vps72p Neighboring gene Vps60p Neighboring gene dynein intermediate chain Neighboring gene DNA replication protein SLD5

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 3,4-dihydroxy-2-butanone-4-phosphate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 3,4-dihydroxy-2-butanone-4-phosphate synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables 3,4-dihydroxy-2-butanone-4-phosphate synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in riboflavin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in riboflavin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in riboflavin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
3,4-dihydroxy-2-butanone-4-phosphate synthase RIB3
NP_010775.1
  • 3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase); required for riboflavin biosynthesis from ribulose-5-phosphate, also has an unrelated function in mitochondrial respiration

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1428354..1428980 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180795.1NP_010775.1  TPA: 3,4-dihydroxy-2-butanone-4-phosphate synthase RIB3 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010775.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTB0, Q99258
    UniProtKB/TrEMBL
    A0A6A5Q2D7, A6ZZ76, B3LFH9, B5VH15, C7GKS5, C8Z645, G2WBL6, N1P7M6
    Conserved Domains (1) summary
    pfam00926
    Location:6205
    DHBP_synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase