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SNF1 AMP-activated serine/threonine-protein kinase catalytic subunit SNF1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852088, updated on 4-Nov-2018

Summary

Gene symbol
SNF1
Gene description
AMP-activated serine/threonine-protein kinase catalytic subunit SNF1
Primary source
SGD:S000002885
Locus tag
YDR477W
Gene type
protein coding
RNA name
AMP-activated serine/threonine-protein kinase catalytic subunit SNF1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CAT1; CCR1; GLC2; HAF3; PAS14

Genomic context

See SNF1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1412373..1414274)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Jip4p Neighboring gene hypothetical protein Neighboring gene Snm1p Neighboring gene Pex29p

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the SNF1 gene: The SNF1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
AMP-activated protein kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
ARF guanyl-nucleotide exchange factor activity IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity HDA PubMed 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to nitrogen starvation IDA
Inferred from Direct Assay
more info
PubMed 
establishment of mitotic spindle orientation IGI
Inferred from Genetic Interaction
more info
PubMed 
establishment of mitotic spindle orientation IMP
Inferred from Mutant Phenotype
more info
PubMed 
fungal-type cell wall assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
invasive growth in response to glucose limitation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of translation IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of filamentous growth of a population of unicellular organisms in response to starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of gluconeogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of macroautophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of pseudohyphal growth IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of pseudohyphal growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein phosphorylation HDA PubMed 
protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
replicative cell aging IGI
Inferred from Genetic Interaction
more info
PubMed 
replicative cell aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to unfolded protein IMP
Inferred from Mutant Phenotype
more info
PubMed 
single-species surface biofilm formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cellular bud neck septin ring IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
fungal-type vacuole IPI
Inferred from Physical Interaction
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion HDA PubMed 
nuclear envelope lumen IDA
Inferred from Direct Assay
more info
PubMed 
nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
nucleotide-activated protein kinase complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide-activated protein kinase complex IPI
Inferred from Physical Interaction
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
AMP-activated serine/threonine-protein kinase catalytic subunit SNF1
NP_010765.3
  • AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1412373..1414274
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180785.3NP_010765.3  TPA: AMP-activated serine/threonine-protein kinase catalytic subunit SNF1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010765.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P06782
    Conserved Domains (3) summary
    cd14079
    Location:52306
    STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase
    pfam08587
    Location:344389
    UBA_2; Ubiquitin associated domain (UBA)
    pfam16579
    Location:504626
    AdenylateSensor; Adenylate sensor of SNF1-like protein kinase
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