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RPB7 DNA-directed RNA polymerase II subunit RPB7 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852013, updated on 6-Jan-2019

Summary

Gene symbol
RPB7
Gene description
DNA-directed RNA polymerase II subunit RPB7
Primary source
SGD:S000002812
Locus tag
YDR404C
Gene type
protein coding
RNA name
DNA-directed RNA polymerase II subunit RPB7
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See RPB7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1276654..1277169, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene putative cytochrome P450 Neighboring gene Dit1p Neighboring gene mitochondrial 54S ribosomal protein YmL41 Neighboring gene ATP-binding cassette multidrug transporter PDR15

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the RPB7 gene: The RPB7 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to DNA-directed 5'-3' RNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA-directed 5'-3' RNA polymerase activity IDA
Inferred from Direct Assay
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
single-stranded DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
single-stranded RNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
translation initiation factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation initiation factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
P-body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
P-body IDA
Inferred from Direct Assay
more info
PubMed 
P-body IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II, core complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA-directed RNA polymerase II subunit RPB7
NP_010692.3
  • RNA polymerase II subunit B16; forms dissociable heterodimer with Rpb4p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNA polymerase II complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1276654..1277169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180712.3NP_010692.3  TPA: DNA-directed RNA polymerase II subunit RPB7 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010692.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34087
    Conserved Domains (1) summary
    COG1095
    Location:1171
    RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]
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