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MCM21 Mcm21p [ Saccharomyces cerevisiae S288c ]

Gene ID: 851916, updated on 8-May-2017
Gene symbol
MCM21
Gene description
Mcm21p
Primary source
SGD:S000002726
Locus tag
YDR318W
Gene type
protein coding
RNA name
Mcm21p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CTF5
See MCM21 in Map Viewer
Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_001136.10 (1103758..1104947)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene gag protein Neighboring gene gag-pol fusion protein Neighboring gene Him1p Neighboring gene Yft2p Neighboring gene Swa2p

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by GO

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
centromere complex assembly IEA
Inferred from Electronic Annotation
more info
 
chromosome segregation IPI
Inferred from Physical Interaction
more info
PubMed 
establishment of mitotic sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to chromosome, centromeric region IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
COMA complex IDA
Inferred from Direct Assay
more info
PubMed 
chromosome IEA
Inferred from Electronic Annotation
more info
 
chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
condensed chromosome kinetochore IEA
Inferred from Electronic Annotation
more info
 
condensed nuclear chromosome kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
kinetochore IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Mcm21p
NP_010604.4
  • Component of the kinetochore sub-complex COMA; COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) bridges kinetochore subunits in contact with centromeric DNA with subunits bound to microtubules during kinetochore assembly; involved in minichromosome maintenance; modified by sumoylation; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-O and fission yeast mal2

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1103758..1104947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180626.3NP_010604.4  TPA: Mcm21p [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_010604.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q06675
    Conserved Domains (1) summary
    pfam09496
    Location:175313
    CENP-O; Cenp-O kinetochore centromere component
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