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SUM1 Sum1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851905, updated on 2-Nov-2024

Summary

Official Symbol
SUM1
Official Full Name
Sum1p
Primary source
SGD:S000002718
Locus tag
YDR310C
See related
AllianceGenome:SGD:S000002718; FungiDB:YDR310C; VEuPathDB:YDR310C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables DNA replication origin binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mitotic cell cycle; negative regulation of macromolecule biosynthetic process; and positive regulation of DNA-templated DNA replication initiation. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See SUM1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1081128..1084316, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Srb7p Neighboring gene Gic2p Neighboring gene TFIIH/NER complex subunit TFB1 Neighboring gene rRNA-binding ribosome biosynthesis protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Sum1p
NP_010596.1
  • Transcriptional repressor that regulates middle-sporulation genes; required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1081128..1084316 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180618.1NP_010596.1  TPA: Sum1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010596.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VST9, P46676
    UniProtKB/TrEMBL
    B3LFY6, C8Z5M1, N1P8L7