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VPS64 Vps64p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851781, updated on 29-Jun-2024

Summary

Gene symbol
VPS64
Gene description
Vps64p
Primary source
FungiDB:YDR200C
Locus tag
YDR200C
See related
SGD:S000002608; AllianceGenome:SGD:S000002608; VEuPathDB:YDR200C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
FAR9
Summary
Involved in TOR signaling and re-entry into mitotic cell cycle after pheromone arrest. Located in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human SLMAP (sarcolemma associated protein). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See VPS64 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (854279..856093, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Cbs2p Neighboring gene protein-lysine N-methyltransferase Neighboring gene Spc19p Neighboring gene Rav2p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
Vps64p
NP_010486.3
  • Protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p and Far7p to Far11p involved in recovery from pheromone-induced cell cycle arrest; mutant has increased aneuploidy tolerance; VPS64 has a paralog, FAR10, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    854279..856093 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180508.3NP_010486.3  TPA: Vps64p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010486.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSI2, Q03944
    UniProtKB/TrEMBL
    A0A8H8UNA8, A6ZYF8, B3LG84, B5VG92, N1P8D8
    Conserved Domains (2) summary
    COG1716
    Location:126304
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    TIGR02168
    Location:406580
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type