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HMO1 Hmo1p [ Saccharomyces cerevisiae S288c ]

Gene ID: 851754, updated on 8-May-2017
Gene symbol
HMO1
Gene description
Hmo1p
Primary source
SGD:S000002581
Locus tag
YDR174W
Gene type
protein coding
RNA name
Hmo1p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HSM2
See HMO1 in Map Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (812110..812850)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene translation termination factor GTPase eRF3 Neighboring gene inositol polyphosphate multikinase Neighboring gene mitochondrial 37S ribosomal protein RSM24 Neighboring gene histone acetyltransferase NGG1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding, bending IDA
Inferred from Direct Assay
more info
PubMed 
double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
four-way junction DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with nuclear chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
rDNA heterochromatin IDA
Inferred from Direct Assay
more info
PubMed 
small-subunit processome IDA
Inferred from Direct Assay
more info
PubMed 
Names
Hmo1p
NP_010459.1
  • Chromatin associated high mobility group (HMG) family member; involved in compacting, bending, bridging and looping DNA; rDNA-binding component that regulates transcription from RNA polymerase I promoters; regulates start site selection of ribosomal protein genes via RNA polymerase II promoters; role in genome maintenance; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase; relocalizes to the cytosol in response to hypoxia

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    812110..812850
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180481.1NP_010459.1  TPA: Hmo1p [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_010459.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q03973
    Conserved Domains (2) summary
    COG5648
    Location:36246
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd01390
    Location:106176
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
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