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SEC1 Sec1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851742, updated on 5-Sep-2021

Summary

Gene symbol
SEC1
Gene description
Sec1p
Primary source
SGD:S000002571
Locus tag
YDR164C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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Genomic context

See SEC1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (782041..784215, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Nbp2p Neighboring gene U2-type spliceosomal complex subunit CWC15 Neighboring gene Trm82p Neighboring gene exocyst subunit SEC5

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the SEC1 gene: The SEC1 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, zebrafish, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables SNARE binding IDA
Inferred from Direct Assay
more info
PubMed 
enables syntaxin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in exocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in exocytosis IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of vesicle fusion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle docking involved in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle docking involved in exocytosis IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Sec1p
NP_010448.1
  • Sm-like protein involved in docking and fusion of exocytic vesicles; binds to assembled SNARE complexes at the membrane and stimulates membrane fusion; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function; interacts directly with essential exocyst subunit Sec6p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    782041..784215 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180471.1NP_010448.1  TPA: Sec1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010448.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30619
    Conserved Domains (1) summary
    COG5158
    Location:1644
    SEC1; Proteins involved in synaptic transmission and general secretion, Sec1 family [Intracellular trafficking and secretion]
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