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DOP1 Dop1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851719, updated on 17-May-2024

Summary

Gene symbol
DOP1
Gene description
Dop1p
Primary source
FungiDB:YDR141C
Locus tag
YDR141C
See related
SGD:S000002548; AllianceGenome:SGD:S000002548; VEuPathDB:YDR141C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in cell morphogenesis; retrograde transport, endosome to Golgi; and retrograde transport, vesicle recycling within Golgi. Located in endosome and trans-Golgi network. Orthologous to several human genes including DOP1B (DOP1 leucine zipper like protein B). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See DOP1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (734901..739997, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene NEDD8 family protein RUB1 Neighboring gene S-adenosylmethionine-dependent methyltransferase Neighboring gene Pex7p Neighboring gene ubiquitin-protein ligase SAN1

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi to endosome transport IEA
Inferred from Electronic Annotation
more info
 
involved_in cell morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, endosome to Golgi IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrograde transport, vesicle recycling within Golgi IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm HDA PubMed 
located_in cytosol HDA PubMed 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Dop1p
NP_010425.1
  • Protein involved in vesicular transport at trans-Golgi network (TGN); TGN-localized, leucine-zipper domain protein; involved in endosome-to-Golgi transport during endocytic recycling, and retrograde transport of glycosyltransferases from the TGN to the Golgi; involved in organization of the ER, establishment of cell polarity, and morphogenesis; detected in highly purified mitochondria in high-throughput studies

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    734901..739997 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180448.1NP_010425.1  TPA: Dop1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010425.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSC4, Q03921
    UniProtKB/TrEMBL
    A0A8H8UN50, C7GIP6, G2WAP1, N1P897
    Conserved Domains (1) summary
    COG5221
    Location:61698
    DOP1; Dopey and related predicted leucine zipper transcription factors [Transcription]