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TRM1 tRNA (guanine26-N2)-dimethyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 851698, updated on 8-Apr-2018
Gene symbol
TRM1
Gene description
tRNA (guanine26-N2)-dimethyltransferase
Primary source
SGD:S000002527
Locus tag
YDR120C
Gene type
protein coding
RNA name
tRNA (guanine26-N2)-dimethyltransferase
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (691549..693261, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Vba4p Neighboring gene Cox26p Neighboring gene DNA polymerase epsilon noncatalytic subunit Neighboring gene serine/threonine protein kinase KIN1

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
tRNA (guanine-N2-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
tRNA (guanine-N2-)-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
tRNA (guanine-N2-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
tRNA (guanine-N2-)-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
methylation IEA
Inferred from Electronic Annotation
more info
 
tRNA N2-guanine methylation IBA
Inferred from Biological aspect of Ancestor
more info
 
tRNA methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
nuclear inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear inner membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
tRNA (guanine26-N2)-dimethyltransferase
NP_010405.3
  • tRNA methyltransferase; two forms of protein are made by alternative translation starts; localizes to both nucleus and mitochondrion to produce modified base N2,N2-dimethylguanosine in tRNAs in both compartments; nuclear Trm1p is evenly distributed around inner nuclear membrane in WT, but mislocalizes as puncta near ER-nucleus junctions in spindle pole body (SPB) mutants; both Trm1p inner nuclear membrane targeting and maintenance depend upon SPB

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    691549..693261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180428.3NP_010405.3  TPA: tRNA (guanine26-N2)-dimethyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010405.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15565
    Conserved Domains (1) summary
    TIGR00308
    Location:45495
    TRM1; tRNA(guanine-26,N2-N2) methyltransferase
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