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BMH2 14-3-3 family protein BMH2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851676, updated on 22-Aug-2021

Summary

Gene symbol
BMH2
Gene description
14-3-3 family protein BMH2
Primary source
SGD:S000002506
Locus tag
YDR099W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SCD3
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Genomic context

See BMH2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (653607..654428)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene gag-pol fusion protein Neighboring gene gag protein Neighboring gene Tvp15p Neighboring gene putative hydrolase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the BMH2 gene: The BMH2 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables DNA replication origin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphoserine residue binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphoserine residue binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in DNA replication initiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in Ras protein signal transduction IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in ascospore formation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cellular protein localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in fungal-type cell wall chitin biosynthetic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of ubiquitin protein ligase activity IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in pre-replicative complex assembly involved in nuclear cell cycle DNA replication IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in pseudohyphal growth IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of glycogen metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in signal transduction involved in filamentous growth IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
14-3-3 family protein BMH2
NP_010384.3
  • 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    653607..654428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180407.3NP_010384.3  TPA: 14-3-3 family protein BMH2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010384.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34730
    Conserved Domains (1) summary
    COG5040
    Location:1273
    BMH1; 14-3-3 family protein [Signal transduction mechanisms]
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