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RPS13 40S ribosomal protein uS15 RPS13 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851636, updated on 15-Feb-2026
Official Symbol
RPS13
Official Full Name
40S ribosomal protein uS15 RPS13
Primary source
SGD:S000002471
Locus tag
YDR064W
See related
AllianceGenome:SGD:S000002471; FungiDB:YDR064W; VEuPathDB:YDR064W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RPS13B; RPS13C
Summary
Enables small ribosomal subunit rRNA binding activity. A structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS13 (ribosomal protein S13). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See RPS13 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_001136.10 (579458..580452)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene serine C-palmitoyltransferase LCB2 Neighboring gene Aim7p Neighboring gene Rrg1p Neighboring gene putative protein-serine/threonine phosphatase

Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of proteins crosslinked to RNA in 40S ribosomal subunits of Saccharomyces cerevisiae. Xiang RH, et al. Biochimie, 1989 Nov-Dec. PMID 2517480
  2. Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit. Min EE, et al. RNA, 2013 Aug. PMID 23801788, Free PMC Article
  3. Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Gerbasi VR, et al. Mol Cell Biol, 2004 Sep. PMID 15340087, Free PMC Article
  4. Yeast Swd2 is essential because of antagonism between Set1 histone methyltransferase complex and APT (associated with Pta1) termination factor. Soares LM, et al. J Biol Chem, 2012 May 4. PMID 22431730, Free PMC Article
  5. Protein topography of the 40 S ribosomal subunit from Saccharomyces cerevisiae as shown by chemical cross-linking. Yeh YC, et al. J Biol Chem, 1986 Oct 25. PMID 3533916

See all (118) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest that ecruitment of COMPASS subunits PMA1 and RPS13 is dependent upon Set1 and Swd2, a subunit of the essential transcription termination factor APT (associated with Pta1).
    Title: Yeast Swd2 is essential because of antagonism between Set1 histone methyltransferase complex and APT (associated with Pta1) termination factor.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables small ribosomal subunit rRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of 90S preribosome HDA PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
40S ribosomal protein uS15 RPS13
NP_010349.3
  • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S13 and bacterial S15

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    579458..580452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180372.3 → NP_010349.3  40S ribosomal protein uS15 RPS13

    See identical proteins and their annotated locations for NP_010349.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VS50, P05756
    UniProtKB/TrEMBL
    A6ZY29, C8Z4Y3, G2WAG8, N1PAC5
    Conserved Domains (1) summary
    PTZ00072
    Location:4 → 151
    PTZ00072; 40S ribosomal protein S13; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P05756.3

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