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NAT1 peptide alpha-N-acetyltransferase complex A subunit NAT1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851521, updated on 5-Sep-2021

Summary

Gene symbol
NAT1
Gene description
peptide alpha-N-acetyltransferase complex A subunit NAT1
Primary source
SGD:S000002198
Locus tag
YDL040C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
AAA1; NAA15
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Genomic context

See NAT1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (378874..381438, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Prp11p Neighboring gene NAD-dependent histone deacetylase SIR2 Neighboring gene pheromone-regulated protein PRM7 Neighboring gene Bsc1p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Component Evidence Code Pubs
part_of NatA complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of NatA complex IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 

General protein information

Preferred Names
peptide alpha-N-acetyltransferase complex A subunit NAT1
NP_010244.1
  • Subunit of protein N-terminal acetyltransferase NatA; NatA comprised of Nat1p, Ard1p, and Nat5p; N-terminally acetylates many proteins to influence multiple processes such as cell cycle progression, heat-shock resistance, mating, sporulation, telomeric silencing and early stages of mitophagy; orthologous to human NAA15; expression of both human NAA10 and NAA15 functionally complements ard1 nat1 double mutant although single mutations are not complemented by their orthologs

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    378874..381438 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180099.1NP_010244.1  TPA: peptide alpha-N-acetyltransferase complex A subunit NAT1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010244.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P12945
    Conserved Domains (3) summary
    COG4783
    Location:1191
    YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
    sd00006
    Location:2448
    TPR; TPR repeat [structural motif]
    pfam12569
    Location:199736
    NARP1; NMDA receptor-regulated protein 1
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