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PRP11 Prp11p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851518, updated on 22-Sep-2022

Summary

Gene symbol
PRP11
Gene description
Prp11p
Primary source
SGD:S000002201
Locus tag
YDL043C
See related
AllianceGenome:SGD:S000002201
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RNA11
Summary
Enables RNA binding activity. Involved in spliceosomal complex assembly. Part of U2-type prespliceosome. Orthologous to human SF3A2 (splicing factor 3a subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See PRP11 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (375680..376480, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene FMN adenylyltransferase Neighboring gene Mtf2p Neighboring gene NAD-dependent histone deacetylase SIR2 Neighboring gene peptide alpha-N-acetyltransferase complex A subunit NAT1

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the PRP11 gene: The PRP11 gene is conserved in rat, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, and N.crassa.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in spliceosomal complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spliceosomal complex assembly IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of U2-type prespliceosome IDA
Inferred from Direct Assay
more info
PubMed 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Prp11p
NP_010241.1
  • Subunit of the SF3a splicing factor complex; required for spliceosome assembly

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    375680..376480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180102.1NP_010241.1  TPA: Prp11p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010241.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q05434, Q07350
    UniProtKB/TrEMBL
    A0A0L8VT85, A0A815XC46, A0A8H8UMN8, B3LGU1, B5VFM4, C7GPW2, C8Z4M7, H0GDU0, N1P7T3
    Conserved Domains (1) summary
    COG5246
    Location:1262
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]