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PBP4 Pbp4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851507, updated on 11-May-2025
Official Symbol
PBP4
Official Full Name
Pbp4p
Primary source
SGD:S000002211
Locus tag
YDL053C
See related
AllianceGenome:SGD:S000002211; FungiDB:YDL053C; VEuPathDB:YDL053C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in cytoplasmic stress granule and peroxisome. [provided by Alliance of Genome Resources, May 2025]
Orthologs
all
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See PBP4 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (361699..362256, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene Mch1p Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase SLC1 Neighboring gene tRNA maturation protein LHP1

Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of factors regulating poly(A) tail synthesis and maturation. Mangus DA, et al. Mol Cell Biol, 2004 May. PMID 15121841, Free PMC Article
  2. Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae. Swisher KD, et al. PLoS One, 2010 Apr 2. PMID 20368989, Free PMC Article
  3. Processing body and stress granule assembly occur by independent and differentially regulated pathways in Saccharomyces cerevisiae. Shah KH, et al. Genetics, 2013 Jan. PMID 23105015, Free PMC Article
  4. Roles for Pbp1 and caloric restriction in genome and lifespan maintenance via suppression of RNA-DNA hybrids. Salvi JS, et al. Dev Cell, 2014 Jul 28. PMID 25073155
  5. Identification of the novel TRAPP associated protein Tca17. Montpetit B, et al. Traffic, 2009 Jun. PMID 19220810

See all (69) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pbp4 and Lsm12 proteins did not dramatically affect the formation of stress granules or P-bodies.
    Title: Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic stress granule HDA PubMed 
located_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
Pbp4p
NP_010230.1
  • Pbp1p binding protein; interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system; also interacts with Lsm12p in a copurification assay; relative distribution to the nucleus increases upon DNA replication stress; also detected in peroxisomes

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    361699..362256 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180112.1 → NP_010230.1  TPA: Pbp4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010230.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRU3, Q07362
    UniProtKB/TrEMBL
    A6ZXS2, B3LGV1, C8Z4L6, N1P631
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07362.1

Gene LinkOut

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