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SYO1 Syo1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851497, updated on 18-Jan-2023

Summary

Gene symbol
SYO1
Gene description
Syo1p
Primary source
SGD:S000002221
Locus tag
YDL063C
See related
AllianceGenome:SGD:S000002221
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables unfolded protein binding activity. Involved in protein import into nucleus and ribosomal large subunit biogenesis. Located in cytoplasm and nucleus. Orthologous to human HEATR3 (HEAT repeat containing 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See SYO1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (338272..340134, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Pex19p Neighboring gene E2 SUMO-conjugating protein UBC9 Neighboring gene ribosomal 40S subunit protein S29B Neighboring gene Tsr1p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables unfolded protein binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein import into nucleus IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosomal large subunit biogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Syo1p
NP_010220.1
  • Transport adaptor or symportin; assembly chaperone that co-translationally associates with nascent Rpl5p, preventing aggregation; facilitates synchronized nuclear coimport of two 5S-rRNA binding proteins, Rpl5p and Rpl11p, mediated by import receptor Kap104p; required for biogenesis of the large ribosomal subunit; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    338272..340134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180122.1NP_010220.1  TPA: Syo1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010220.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q07395, Q7LGT0
    UniProtKB/TrEMBL
    A0A8H8UML9, B3LGW0, C7GJP6, C8Z4K6, H0GDS5, N1PAA1
    Conserved Domains (1) summary
    cd13394
    Location:15615
    Syo1_like; Fungal symportin 1 (syo1) and similar proteins