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COX9 cytochrome c oxidase subunit VIIa [ Saccharomyces cerevisiae S288C ]

Gene ID: 851492, updated on 6-Jul-2026
Official Symbol
COX9
Official Full Name
cytochrome c oxidase subunit VIIa
Primary source
SGD:S000002225
Locus tag
YDL067C
See related
AllianceGenome:SGD:S000002225; FungiDB:YDL067C; VEuPathDB:YDL067C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Contributes to cytochrome-c oxidase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of respiratory chain complex IV. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See COX9 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (334217..334396, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Bdf2p Neighboring gene Cbs1p Neighboring gene isocitrate dehydrogenase (NADP(+)) IDP1 Neighboring gene Pex19p

Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization of Paracoccidioides brasiliensis COX9, COX12, and COX16 respiratory genes. Bandeira SC, et al. Mycol Res, 2008 Dec. PMID 18672058
  2. Mitochondrial import of cytochrome c oxidase subunit VIIa in Saccharomyces cerevisiae. Identification of sequences required for mitochondrial localization in vivo. Duhl DM, et al. J Biol Chem, 1990 May 5. PMID 2158998
  3. Characterization of COX9, the nuclear gene encoding the yeast mitochondrial protein cytochrome c oxidase subunit VIIa. Subunit VIIa lacks a leader peptide and is an essential component of the holoenzyme. Wright RM, et al. J Biol Chem, 1986 Dec 25. PMID 3023385
  4. Subunits Rip1p and Cox9p of the respiratory chain contribute to diclofenac-induced mitochondrial dysfunction. van Leeuwen JS, et al. Microbiology (Reading), 2011 Mar. PMID 21148204
  5. Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae. Characterization of mutants in 34 complementation groups. McEwen JE, et al. J Biol Chem, 1986 Sep 5. PMID 3017950

See all (69) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to cytochrome-c oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to cytochrome-c oxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial electron transport, cytochrome c to oxygen IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial electron transport, cytochrome c to oxygen IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
Inferred from Electronic Annotation
more info
  
involved_in oxidative phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane EXP
Inferred from Experiment
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
part_of respiratory chain complex IV IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
cytochrome c oxidase subunit VIIa
NP_010216.1
  • Subunit VIIa of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    334217..334396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180126.1 → NP_010216.1  cytochrome c oxidase subunit VIIa

    See identical proteins and their annotated locations for NP_010216.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRT0, P07255
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07255.2

Gene LinkOut

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