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RPO21 DNA-directed RNA polymerase II core subunit RPO21 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851415, updated on 9-Dec-2017
Gene symbol
RPO21
Gene description
DNA-directed RNA polymerase II core subunit RPO21
Primary source
SGD:S000002299
Locus tag
YDL140C
Gene type
protein coding
RNA name
DNA-directed RNA polymerase II core subunit RPO21
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RPB1; RPB220; SUA8
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (205360..210561, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene cardiolipin synthase Neighboring gene biotin--[acetyl-CoA-carboxylase] ligase BPL1 Neighboring gene Scm3p Neighboring gene glucose sensor

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase II activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to RNA-directed 5'-3' RNA polymerase activity IDA
Inferred from Direct Assay
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, RNA-templated IEA
Inferred from Electronic Annotation
more info
 
translesion synthesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
DNA-directed RNA polymerase II, core complex IDA
Inferred from Direct Assay
more info
PubMed 
DNA-directed RNA polymerase II, core complex IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
DNA-directed RNA polymerase II core subunit RPO21
NP_010141.1
  • RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    205360..210561 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180200.1NP_010141.1  TPA: DNA-directed RNA polymerase II core subunit RPO21 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010141.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P04050
    Conserved Domains (3) summary
    cd02584
    Location:10351446
    RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain
    cd02733
    Location:15853
    RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain
    pfam04992
    Location:8731056
    RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6
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