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PRR2 serine/threonine protein kinase PRR2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851312, updated on 18-Jan-2023

Summary

Gene symbol
PRR2
Gene description
serine/threonine protein kinase PRR2
Primary source
SGD:S000002373
Locus tag
YDL214C
See related
AllianceGenome:SGD:S000002373
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables protein kinase activity. Involved in negative regulation of conjugation with cellular fusion and negative regulation of transcription from RNA polymerase II promoter by pheromones. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See PRR2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (74446..76545, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene COP9 signalosome catalytic subunit RRI1 Neighboring gene glutamate dehydrogenase (NAD(+)) Neighboring gene Nop6p Neighboring gene Shr3p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity HDA PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
serine/threonine protein kinase PRR2
NP_010067.1
  • Serine/threonine protein kinase; inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance; PRR2 has a paralog, NPR1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    74446..76545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180274.1NP_010067.1  TPA: serine/threonine protein kinase PRR2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010067.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRE0, Q12310
    UniProtKB/TrEMBL
    A0A8H8UM87, N1P4M6
    Conserved Domains (1) summary
    cl21453
    Location:367653
    PKc_like; Protein Kinases, catalytic domain