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PHO11 acid phosphatase PHO11 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851299, updated on 8-Feb-2025

Summary

Official Symbol
PHO11
Official Full Name
acid phosphatase PHO11
Primary source
SGD:S000000094
Locus tag
YAR071W
See related
AllianceGenome:SGD:S000000094; FungiDB:YAR071W; VEuPathDB:YAR071W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables acid phosphatase activity. Predicted to be involved in phosphate-containing compound metabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma and pontocerebellar hypoplasia type 16. Orthologous to human MINPP1 (multiple inositol-polyphosphate phosphatase 1). [provided by Alliance of Genome Resources, Feb 2025]
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Genomic context

See PHO11 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_001133.9 (225460..226863)

Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables acid phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acid phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables acid phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in phosphate-containing compound metabolic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in fungal-type cell wall IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
acid phosphatase PHO11
NP_009434.1
  • One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001133.9 Reference assembly

    Range
    225460..226863
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178239.1NP_009434.1  TPA: acid phosphatase PHO11 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009434.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPP1, P35842
    UniProtKB/TrEMBL
    A6ZSK2, B5VKE4
    Conserved Domains (1) summary
    pfam00328
    Location:65399
    His_Phos_2; Histidine phosphatase superfamily (branch 2)