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DEP1 Rpd3L histone deacetylase complex subunit DEP1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851220, updated on 5-Nov-2017
Gene symbol
DEP1
Gene description
Rpd3L histone deacetylase complex subunit DEP1
Primary source
SGD:S000000011
Locus tag
YAL013W
Gene type
protein coding
RNA name
Rpd3L histone deacetylase complex subunit DEP1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
FUN54
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_001133.9 (129270..130487)

Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene bifunctional N-glycosylase/AP lyase NTG1 Neighboring gene syntaxin Neighboring gene cystathionine gamma-lyase CYS3 Neighboring gene Swc3p

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to histone deacetylase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
covalent chromatin modification IEA
Inferred from Electronic Annotation
more info
 
histone deacetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of chromatin silencing at rDNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of chromatin silencing at silent mating-type cassette IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of chromatin silencing at telomere IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of chromatin silencing at telomere IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of chromatin silencing at telomere IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of phosphatidylcholine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter in response to heat stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of DNA-dependent DNA replication initiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Rpd3L complex IDA
Inferred from Direct Assay
more info
PubMed 
Rpd3L-Expanded complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Rpd3L histone deacetylase complex subunit DEP1
NP_009389.3
  • Component of the Rpd3L histone deacetylase complex; required for diauxic shift-induced histone H2B deposition onto rDNA genes; transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001133.9 Reference assembly

    Range
    129270..130487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178158.2NP_009389.3  TPA: Rpd3L histone deacetylase complex subunit DEP1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009389.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P31385
    Conserved Domains (1) summary
    pfam08598
    Location:182402
    Sds3; Sds3-like
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