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LSM3 U4/U6-U5 snRNP complex subunit LSM3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851159, updated on 7-Oct-2018

Summary

Gene symbol
LSM3
Gene description
U4/U6-U5 snRNP complex subunit LSM3
Primary source
SGD:S000006434
Locus tag
YLR438C-A
Gene type
protein coding
RNA name
U4/U6-U5 snRNP complex subunit LSM3
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SMX4; USS2

Genomic context

See LSM3 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (1013909..1014178, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Dif1p Neighboring gene ornithine-oxo-acid transaminase Neighboring gene mitochondrial 54S ribosomal protein YmL4 Neighboring gene Sec39p

Bibliography

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic mRNA processing body assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 
mRNA splicing, via spliceosome IPI
Inferred from Physical Interaction
more info
PubMed 
nuclear-transcribed mRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Lsm1-7-Pat1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Lsm1-7-Pat1 complex IDA
Inferred from Direct Assay
more info
PubMed 
P-body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
U4/U6 x U5 tri-snRNP complex IDA
Inferred from Direct Assay
more info
PubMed 
U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
U6 snRNP IDA
Inferred from Direct Assay
more info
PubMed 
catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm HDA PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus HDA PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
small nucleolar ribonucleoprotein complex IPI
Inferred from Physical Interaction
more info
PubMed 
spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
U4/U6-U5 snRNP complex subunit LSM3
NP_013543.3
  • Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein increases in abundance and relocalizes from nucleus to cytoplasmic foci upon DNA replication stress

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    1013909..1014178 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184308.3NP_013543.3  TPA: U4/U6-U5 snRNP complex subunit LSM3 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013543.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P57743
    Conserved Domains (1) summary
    cd01730
    Location:478
    LSm3; Like-Sm protein 3
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