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ROM2 Rho family guanine nucleotide exchange factor ROM2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851086, updated on 5-Sep-2021

Summary

Gene symbol
ROM2
Gene description
Rho family guanine nucleotide exchange factor ROM2
Primary source
SGD:S000004363
Locus tag
YLR371W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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Genomic context

See ROM2 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (862714..866784)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Hsp70 family ATPase SSQ1 Neighboring gene Arc18p Neighboring gene fatty acid elongase ELO3 Neighboring gene Vid22p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the ROM2 gene: The ROM2 gene is conserved in S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, and N.crassa.

Gene Ontology Provided by GO

General protein information

Preferred Names
Rho family guanine nucleotide exchange factor ROM2
NP_013475.1
  • Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEF; Rom2p localization to the bud surface is dependent on Ack1p; ROM2 has a paralog, ROM1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    862714..866784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182260.1NP_013475.1  TPA: Rho family guanine nucleotide exchange factor ROM2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013475.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P51862
    Conserved Domains (1) summary
    COG5422
    Location:41356
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
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