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BUD6 Bud6p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851029, updated on 8-Aug-2021

Summary

Gene symbol
BUD6
Gene description
Bud6p
Primary source
SGD:S000004311
Locus tag
YLR319C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
AIP3
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Genomic context

See BUD6 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (769318..771684, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Nkp2p Neighboring gene Tad3p Neighboring gene telomerase reverse transcriptase Neighboring gene Mms22p Neighboring gene Sfh1p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables actin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cytoskeletal regulatory protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cytoskeletal regulatory protein binding IEA
Inferred from Electronic Annotation
more info
 
enables cytoskeletal regulatory protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables enzyme activator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in actin filament bundle assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in actin filament bundle assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in astral microtubule organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in bipolar cellular bud site selection IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in budding cell apical bud growth IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in budding cell apical bud growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in establishment of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in extrachromosomal circular DNA localization involved in cell aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of actin cytoskeleton reorganization IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of actin cytoskeleton reorganization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of actin nucleation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of actin nucleation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of formin-nucleated actin cable assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of formin-nucleated actin cable assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in pseudohyphal growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of actin nucleation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell tip IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cellular bud neck IDA
Inferred from Direct Assay
more info
PubMed 
located_in cellular bud tip IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of incipient cellular bud site IDA
Inferred from Direct Assay
more info
PubMed 
located_in mating projection tip HDA PubMed 
located_in mating projection tip IDA
Inferred from Direct Assay
more info
PubMed 
part_of polarisome IDA
Inferred from Direct Assay
more info
PubMed 
located_in prospore membrane HDA PubMed 
located_in secretory vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in spindle pole body IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Bud6p
NP_013423.1
  • Actin- and formin-interacting protein; nucleation-promoting factor (NPF) for Bni1p and Bnr1p during actin cable assembly and organization; enhances Bnr1p-mediated actin nucleation, alleviating Hof1p inhibition through competitive binding; interacts with Bni1p via a C-terminal triple helical coiled-coil domain; role in polarized cell growth; isolated as a bipolar budding mutant; localizes to the presumptive bud site, small bud tips, the bud neck and secretory vesicles; potential Cdc28p substrate

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    769318..771684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182208.1NP_013423.1  TPA: Bud6p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013423.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P41697
    Conserved Domains (1) summary
    smart00806
    Location:365776
    AIP3; Actin interacting protein 3
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