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YPT6 Rab family GTPase YPT6 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850966, updated on 4-Aug-2021

Summary

Gene symbol
YPT6
Gene description
Rab family GTPase YPT6
Primary source
SGD:S000004252
Locus tag
YLR262C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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Genomic context

See YPT6 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (668244..668891, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene chaperone ATPase HSP60 Neighboring gene sphinganine kinase LCB5 Neighboring gene Vps63p Neighboring gene Tma7p Neighboring gene Red1p

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the YPT6 gene: The YPT6 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in Golgi to endosome transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular protein-containing complex localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cytoplasm to vacuole transport by the Cvt pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in macroautophagy IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in macroautophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein localization to phagophore assembly site IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retrograde transport, endosome to Golgi IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in retrograde transport, endosome to Golgi IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrograde transport, vesicle recycling within Golgi IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in cis-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Rab family GTPase YPT6
NP_013363.1
  • Rab family GTPase; required for endosome-to-Golgi, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    668244..668891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182149.1NP_013363.1  TPA: Rab family GTPase YPT6 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013363.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q99260
    Conserved Domains (1) summary
    cd01861
    Location:11173
    Rab6; Rab GTPase family 6 (Rab6)
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