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RRN5 Rrn5p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850832, updated on 14-Nov-2024

Summary

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Official Symbol
RRN5
Official Full Name
Rrn5p
Primary source
SGD:S000004131
Locus tag
YLR141W
See related
AllianceGenome:SGD:S000004131; FungiDB:YLR141W; VEuPathDB:YLR141W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables RNA polymerase I general transcription initiation factor activity. Involved in chromatin organization and nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus. Part of RNA polymerase I upstream activating factor complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RRN5 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (423683..424774)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Nha1p Neighboring gene Sls1p Neighboring gene proline dehydrogenase Neighboring gene tRNA-Asp

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DNA protein-interactions at the Saccharomyces cerevisiae 35 S rRNA promoter and in its surrounding region. Vogelauer M, et al. J Mol Biol, 1998 Jan 16. PMID 9466903
  2. RNA polymerase switch in transcription of yeast rDNA: role of transcription factor UAF (upstream activation factor) in silencing rDNA transcription by RNA polymerase II. Vu L, et al. Proc Natl Acad Sci U S A, 1999 Apr 13. PMID 10200272, Free PMC Article
  3. Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Keys DA, et al. Genes Dev, 1996 Apr 1. PMID 8846924
  4. Histones are required for transcription of yeast rRNA genes by RNA polymerase I. Tongaonkar P, et al. Proc Natl Acad Sci U S A, 2005 Jul 19. PMID 16002464, Free PMC Article
  5. Histones H3 and H4 are components of upstream activation factor required for the high-level transcription of yeast rDNA by RNA polymerase I. Keener J, et al. Proc Natl Acad Sci U S A, 1997 Dec 9. PMID 9391047, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA polymerase I general transcription initiation factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables rDNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleolar large rRNA transcription by RNA polymerase I IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in nucleolar large rRNA transcription by RNA polymerase I IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleolar large rRNA transcription by RNA polymerase I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation at RNA polymerase I promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of RNA polymerase I upstream activating factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase I upstream activating factor complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase I upstream activating factor complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rrn5p
NP_013242.1
  • Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    423683..424774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182028.1 → NP_013242.1  TPA: Rrn5p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013242.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYD5, Q02983, Q12061
    UniProtKB/TrEMBL
    C8ZDB0, N1P6N4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02983.1

Gene LinkOut

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