U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

AVL9 Avl9p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850805, updated on 6-Jul-2026
Official Symbol
AVL9
Official Full Name
Avl9p
Primary source
SGD:S000004104
Locus tag
YLR114C
See related
AllianceGenome:SGD:S000004104; FungiDB:YLR114C; VEuPathDB:YLR114C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in post-Golgi vesicle-mediated transport. Located in cellular bud neck; cellular bud tip; and cytoplasm. Orthologous to human AVL9 (AVL9 cell migration associated). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See AVL9 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (374944..377238, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase HOG1 Neighboring gene tRNA-Arg Neighboring gene cleavage polyadenylation factor subunit CFT2 Neighboring gene mRNA splicing protein MSL5

Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway. Harsay E, et al. Mol Biol Cell, 2007 Apr. PMID 17229886, Free PMC Article
  2. Sequence analysis of a 37.6 kbp cosmid clone from the right arm of Saccharomyces cerevisiae chromosome XII, carrying YAP3, HOG1, SNR6, tRNA-Arg3 and 23 new open reading frames, among which several homologies to proteins involved in cell division control and to mammalian growth factors and other animal proteins are found. Verhasselt P, et al. Yeast, 1997 Mar 15. PMID 9090053
  3. The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p. Shen D, et al. J Cell Biol, 2013 Aug 5. PMID 23897890, Free PMC Article
  4. A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis. Singh J, et al. Genes Dev, 2009 Aug 15. PMID 19684114, Free PMC Article
  5. Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase. Wood CS, et al. Mol Biol Cell, 2012 Jul. PMID 22553352, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AVL9 plays role in Golgi apparatus and exocytosis
    Title: Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in post-Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cellular bud neck HDA PubMed 
located_in cellular bud tip HDA PubMed 
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Avl9p
NP_013215.1
  • Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    374944..377238 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182001.1 → NP_013215.1  Avl9p

    See identical proteins and their annotated locations for NP_013215.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYB2, Q12500
    UniProtKB/TrEMBL
    B3LT79
    Conserved Domains (1) summary
    pfam09794
    Location:9 → 401
    Avl9; Transport protein Avl9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12500.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools