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SIC1 cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850768, updated on 4-Aug-2021

Summary

Gene symbol
SIC1
Gene description
cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1
Primary source
SGD:S000004069
Locus tag
YLR079W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
BYC1; SDB25
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Genomic context

See SIC1 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (286820..287674)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Fmp25p Neighboring gene Bos1p Neighboring gene Emp46p Neighboring gene galactose permease GAL2

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1
NP_013180.1
  • Cyclin-dependent kinase inhibitor (CKI); inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylated by Clb5/6-Cdk1 and Cln1/2-Cdk1 kinase which regulate timing of Sic1p degradation; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    286820..287674
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181966.1NP_013180.1  TPA: cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013180.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38634
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