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RLP24 ATPase-activating ribosome biosynthesis protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 850695, updated on 3-Jun-2026
Official Symbol
RLP24
Official Full Name
ATPase-activating ribosome biosynthesis protein
Primary source
SGD:S000003999
Locus tag
YLR009W
See related
AllianceGenome:SGD:S000003999; FungiDB:YLR009W; VEuPathDB:YLR009W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables ATPase activator activity. Involved in assembly of large subunit precursor of preribosome. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to human RSL24D1 (ribosomal L24 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (166537..167136)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Smc5-Smc6 complex subunit NSE1 Neighboring gene Pam18p Neighboring gene Ten1p Neighboring gene tRNA-Ser

Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1. Pertschy B, et al. Mol Cell Biol, 2007 Oct. PMID 17646390, Free PMC Article
  2. Integrity of the P-site is probed during maturation of the 60S ribosomal subunit. Bussiere C, et al. J Cell Biol, 2012 Jun 11. PMID 22689654, Free PMC Article
  3. Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. Lebreton A, et al. J Biol Chem, 2006 Sep 15. PMID 16861225
  4. Ribosome stalk assembly requires the dual-specificity phosphatase Yvh1 for the exchange of Mrt4 with P0. Lo KY, et al. J Cell Biol, 2009 Sep 21. PMID 19797078, Free PMC Article
  5. Functional redundancy of yeast proteins Reh1 and Rei1 in cytoplasmic 60S subunit maturation. Parnell KM, et al. Mol Cell Biol, 2009 Jul. PMID 19433447, Free PMC Article

See all (103) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATPase activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATPase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in assembly of large subunit precursor of preribosome IEA
Inferred from Electronic Annotation
more info
  
involved_in assembly of large subunit precursor of preribosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of ATP-dependent activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm EXP
Inferred from Experiment
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus EXP
Inferred from Experiment
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome, large subunit precursor HDA PubMed 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 
part_of preribosome, large subunit precursor IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Preferred Names
ATPase-activating ribosome biosynthesis protein
NP_013109.1
  • Essential protein required for ribosomal large subunit biogenesis; associated with pre-60S ribosomal subunits; stimulates the ATPase activity of Afg2p, which is required for release of Rlp24p from the pre-60S particle; has similarity to Rpl24Ap and Rpl24Bp

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    166537..167136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181896.1 → NP_013109.1  ATPase-activating ribosome biosynthesis protein

    See identical proteins and their annotated locations for NP_013109.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VY11, Q07915
    UniProtKB/TrEMBL
    A7A0R4, B3LSY2, B5VMV1, C7GPE9, C8ZCY1, G2WIK3, N1NYZ6
    Conserved Domains (1) summary
    pfam01246
    Location:2 → 64
    Ribosomal_L24e; Ribosomal protein L24e
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07915.1

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