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SSK1 mitogen-activated protein kinase kinase kinase SSK1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850692, updated on 12-Aug-2021

Summary

Gene symbol
SSK1
Gene description
mitogen-activated protein kinase kinase kinase SSK1
Primary source
SGD:S000003996
Locus tag
YLR006C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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Genomic context

See SSK1 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (161755..163893, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Thi73p Neighboring gene TFIIH/NER complex subunit SSL1 Neighboring gene Smc5-Smc6 complex subunit NSE1 Neighboring gene Pam18p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables mitogen-activated protein kinase kinase kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables phosphorelay response regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphorelay response regulator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein kinase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein kinase activator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of Mcs4 RR-MAPKKK complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mitogen-activated protein kinase kinase kinase SSK1
NP_013106.1
  • Cytoplasmic phosphorelay intermediate osmosensor and regulator; part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; required for mitophagy; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    161755..163893 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181893.1NP_013106.1  TPA: mitogen-activated protein kinase kinase kinase SSK1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013106.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q07084
    Conserved Domains (1) summary
    cd17546
    Location:506643
    REC_hyHK_CKI1_RcsC-like; phosphoacceptor receiver (REC) domain of hybrid sensor histidine kinases/response regulators similar to Arabidopsis thaliana CKI1 and Escherichia coli RcsC
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