POM33 nucleoporin POM33 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: POM33
Official Full Name: nucleoporin POM33
Primary source: SGD:S000003946
Locus tag: YLL023C
See related: AllianceGenome:SGD:S000003946; FungiDB:YLL023C; VEuPathDB:YLL023C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Involved in nuclear pore localization and nuclear pore organization. Located in endoplasmic reticulum. Part of nuclear pore. Is active in nuclear envelope. Orthologous to human TMEM33 (transmembrane protein 33). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Chromosome XII - NC_001144.5 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum tubular network organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA transport	IEA Inferred from Electronic Annotation more info
involved_in membrane organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in nuclear pore localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear pore organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	HDA more info	PubMed
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in nuclear envelope	IDA Inferred from Direct Assay more info	PubMed
located_in nuclear outer membrane	ISM Inferred from Sequence Model more info	PubMed
part_of nuclear pore	IDA Inferred from Direct Assay more info	PubMed
part_of nuclear pore	IEA Inferred from Electronic Annotation more info

NP_013077.1

Transmembrane nucleoporin; involved in nuclear pore complex (NPC) distribution, assembly or stabilization; highly conserved across species, orthologous to human TMEM33 and paralogous to Per33p; protein abundance increases in response to DNA replication stress