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RIX7 putative AAA family ATPase RIX7 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850625, updated on 18-Jan-2023

Summary

Gene symbol
RIX7
Gene description
putative AAA family ATPase RIX7
Primary source
SGD:S000003957
Locus tag
YLL034C
See related
AllianceGenome:SGD:S000003957
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable ATP hydrolysis activity and preribosome binding activity. Involved in ribosomal large subunit biogenesis and ribosomal large subunit export from nucleus. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to human NVL (nuclear VCP like). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See RIX7 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (70633..73146, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase PRP19 Neighboring gene polynucleotide 5'-hydroxyl-kinase Neighboring gene Irc19p Neighboring gene uncharacterized protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the RIX7 gene: The RIX7 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables preribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of telomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosomal large subunit biogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in ribosomal large subunit biogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ribosomal large subunit export from nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleolus HDA PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
putative AAA family ATPase RIX7
NP_013066.1
  • Putative ATPase of the AAA family; required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    70633..73146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181854.1NP_013066.1  TPA: putative AAA family ATPase RIX7 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013066.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXX1, Q07844
    UniProtKB/TrEMBL
    A0A8H4BZ25, N1P6V6
    Conserved Domains (1) summary
    TIGR01243
    Location:192824
    CDC48; AAA family ATPase, CDC48 subfamily