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UBI4 ubiquitin [ Saccharomyces cerevisiae S288C ]

Gene ID: 850620, updated on 5-Jul-2025
Official Symbol
UBI4
Official Full Name
ubiquitin
Primary source
SGD:S000003962
Locus tag
YLL039C
See related
AllianceGenome:SGD:S000003962; FungiDB:YLL039C; VEuPathDB:YLL039C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SCD2; UB14
Summary
Enables protein tag activity. Involved in protein ubiquitination. Located in peroxisome. Orthologous to human UBC (ubiquitin C). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
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See UBI4 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (64062..65207, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene succinate dehydrogenase iron-sulfur protein subunit SDH2 Neighboring gene membrane morphogenesis protein VPS13 Neighboring gene Ent4p Neighboring gene E3 ubiquitin-protein ligase PRP19

Genomic Sequence:
NC_001144.5

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables protein tag activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein tag activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein tag activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in modification-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in protein ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in peroxisome IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
ubiquitin
NP_013061.1
  • Ubiquitin; becomes conjugated to proteins, marking them for selective degradation via ubiquitin-26S proteasome system; essential for cellular stress response; encoded as polyubiquitin precursor comprised of 5 head-to-tail repeats; number of repeats is evolutionarily unstable within and between yeast species; protein abundance increases in response to DNA replication stress; implicated as modulator of replicative lifespan and meiotic recombination

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    64062..65207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181859.1NP_013061.1  TPA: ubiquitin

    See identical proteins and their annotated locations for NP_013061.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXW7, P0CG63
    UniProtKB/TrEMBL
    A7A0L9, B3LTD4, C8ZCT5, G2WIF8
    Conserved Domains (1) summary
    cd01803
    Location:77152
    Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin