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YFH7 Yfh7p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850558, updated on 6-Jul-2026
Official Symbol
YFH7
Official Full Name
Yfh7p
Primary source
SGD:S000001903
Locus tag
YFR007W
See related
AllianceGenome:SGD:S000001903; FungiDB:YFR007W; VEuPathDB:YFR007W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
AIM12
Summary
Enables ATP hydrolysis activity. Predicted to be involved in phosphorylation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See YFH7 in Genome Data Viewer
Location:
chromosome: VI
Exon count:
1
Sequence:
Chromosome: VI; NC_001138.5 (159299..160360)

Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene putative Xaa-Pro dipeptidase Neighboring gene tRNA-Phe Neighboring gene Far7p Neighboring gene tRNA-Gly

Genomic Sequence:
NC_001138.5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Crystal structure and functional analysis identify the P-loop containing protein YFH7 of Saccharomyces cerevisiae as an ATP-dependent kinase. Gueguen-Chaignon V, et al. Proteins, 2008 May 1. PMID 18004758
  2. Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. Murakami Y, et al. Nat Genet, 1995 Jul. PMID 7670463
  3. Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. McClellan AJ, et al. Cell, 2007 Oct 5. PMID 17923092
  4. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Ito T, et al. Proc Natl Acad Sci U S A, 2001 Apr 10. PMID 11283351, Free PMC Article
  5. Pervasive and dynamic protein binding sites of the mRNA transcriptome in Saccharomyces cerevisiae. Freeberg MA, et al. Genome Biol, 2013 Feb 14. PMID 23409723, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
Yfh7p
NP_116662.1
  • Putative kinase with similarity to the PRK/URK/PANK kinase subfamily; the PRK/URK/PANK subfamily of P-loop kinases is also known as phosphoribulokinase/uridine kinase/bacterial pantothenate kinase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001138.5 Reference assembly

    Range
    159299..160360
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179972.1 → NP_116662.1  Yfh7p

    See identical proteins and their annotated locations for NP_116662.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A7A245, B3LUL5, B5VI33, D6VTN7, P43591
    Conserved Domains (1) summary
    COG1072
    Location:21 → 353
    CoaA; Panthothenate kinase [Coenzyme transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43591.1

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