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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 850503, updated on 7-Apr-2025

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000001854
Locus tag
YFL040W
See related
AllianceGenome:SGD:S000001854; FungiDB:YFL040W; VEuPathDB:YFL040W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol import across plasma membrane. Located in fungal-type vacuole and prospore membrane. [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
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Genomic context

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Location:
chromosome: VI
Exon count:
1
Sequence:
Chromosome: VI; NC_001138.5 (51350..52972)

Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ferroxidase FET5 Neighboring gene actin Neighboring gene Rab family GTPase YPT1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001138.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Improvement of acetic acid tolerance of Saccharomyces cerevisiae using a zinc-finger-based artificial transcription factor and identification of novel genes involved in acetic acid tolerance. Ma C, et al. Appl Microbiol Biotechnol, 2015 Mar. PMID 25698512
  2. The genetic basis of natural variation in oenological traits in Saccharomyces cerevisiae. Salinas F, et al. PLoS One, 2012. PMID 23185390, Free PMC Article
  3. A phylogenetic analysis of the sugar porters in hemiascomycetous yeasts. Palma M, et al. J Mol Microbiol Biotechnol, 2007. PMID 17587872
  4. Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae. Sullivan DP, et al. Eukaryot Cell, 2009 Feb. PMID 19060182, Free PMC Article
  5. A nutrient-responsive pathway that determines M phase timing through control of B-cyclin mRNA stability. Messier V, et al. Cell, 2013 May 23. PMID 23706744

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables myo-inositol:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in myo-inositol import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in fungal-type vacuole HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in prospore membrane HDA PubMed 

General protein information

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Preferred Names
uncharacterized protein
NP_116613.1
  • Putative transporter; member of the sugar porter family; YFL040W is not an essential gene; may have a role in intracellular sterol transport

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001138.5 Reference assembly

    Range
    51350..52972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179926.1 → NP_116613.1  TPA: uncharacterized protein YFL040W [Saccharomyces cerevisiae S288C]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTJ0, P43562
    UniProtKB/TrEMBL
    G2WDA1, N1P325
    Conserved Domains (1) summary
    cd17356
    Location:28 → 490
    MFS_HXT; Fungal Hexose transporter subfamily of the Major Facilitator Superfamily of transporters and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43562.1

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