RBK1 putative ribokinase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: RBK1
Official Full Name: putative ribokinase
Primary source: SGD:S000000632
Locus tag: YCR036W
See related: AllianceGenome:SGD:S000000632; FungiDB:YCR036W; VEuPathDB:YCR036W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable ribokinase activity. Predicted to be involved in D-ribose catabolic process. Located in cytoplasm and nucleus. Orthologous to human RBKS (ribokinase). [provided by Alliance of Genome Resources, Mar 2025]
Orthologs: all
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Genomic context

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See RBK1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 1

Sequence:: Chromosome: III; NC_001135.5 (193297..194298)

Chromosome III - NC_001135.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ribokinase activity	IEA Inferred from Electronic Annotation more info
enables ribokinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within D-ribose catabolic process	IEA Inferred from Electronic Annotation more info
involved_in D-ribose catabolic process	ISS Inferred from Sequence or Structural Similarity more info	PubMed
acts_upstream_of_or_within D-ribose metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within carbohydrate phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within small molecule metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	HDA more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative ribokinase

NP_009965.2

EC 2.7.1.15

Ribokinase, phosphorylates ribose to ribose-5-phosphate; required for recycling ribose during nucleotide metabolism

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001135.5 Reference assembly

Range

193297..194298

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001178750.1 → NP_009965.2 TPA: putative ribokinase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_009965.2

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VR46, P25332

UniProtKB/TrEMBL

B3LUA5, B5VEY0

Conserved Domains (1) summary

cd01174
Location:2 → 324

ribokinase; Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides ...