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CTO1 Cto1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850373, updated on 24-Jan-2026
Official Symbol
CTO1
Official Full Name
Cto1p
Primary source
SGD:S000000608
Locus tag
YCR015C
See related
AllianceGenome:SGD:S000000608; FungiDB:YCR015C; VEuPathDB:YCR015C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables thiamine phosphate phosphatase activity. Involved in phosphate ion transport. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See CTO1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (141217..142170, complement)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene phosphoglycerate kinase Neighboring gene DNA-directed DNA polymerase IV Neighboring gene ncRNA Neighboring gene tRNA-Gly

Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cell-Cycle Modulation of Transcription Termination Factor Sen1. Mischo HE, et al. Mol Cell, 2018 Apr 19. PMID 29656924, Free PMC Article
  2. Genetic evidence that Ras-like GTPases, Gtr1p, and Gtr2p, are involved in epigenetic control of gene expression in Saccharomyces cerevisiae. Sekiguchi T, et al. Biochem Biophys Res Commun, 2008 Apr 11. PMID 18258182
  3. Uptake of inorganic phosphate is a limiting factor for Saccharomyces cerevisiae during growth at low temperatures. Vicent I, et al. FEMS Yeast Res, 2015 May. PMID 25725023
  4. Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS. Kuznetsova E, et al. J Biol Chem, 2015 Jul 24. PMID 26071590, Free PMC Article
  5. Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes. del Alamo M, et al. PLoS Biol, 2011 Jul. PMID 21765803, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables thiamine phosphate phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphate ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
Preferred Names
Cto1p
NP_009941.2
  • Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    141217..142170 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178728.1 → NP_009941.2  Cto1p

    See identical proteins and their annotated locations for NP_009941.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR23, P25616, Q8NIM3
    UniProtKB/TrEMBL
    A6ZTJ5, B3LU85, B5VEW2, C7GQM6, C8Z4A2, G2WA31, N1P7U7
    Conserved Domains (1) summary
    cl21460
    Location:128 → 237
    HAD_like; Haloacid Dehalogenase-like Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25616.2

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