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GLK1 glucokinase [ Saccharomyces cerevisiae S288C ]

Gene ID: 850317, updated on 3-Sep-2017
Gene symbol
GLK1
Gene description
glucokinase
Primary source
SGD:S000000545
Locus tag
YCL040W
Gene type
protein coding
RNA name
glucokinase
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HOR3
See GLK1 in Map Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (50838..52340)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene Mgr1p Neighboring gene protein disulfide isomerase PDI1 Neighboring gene hypothetical protein Neighboring gene glucose-induced degradation complex subunit GID7 Neighboring gene Atg22p

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
fructokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
glucokinase activity IDA
Inferred from Direct Assay
more info
PubMed 
glucokinase activity IEA
Inferred from Electronic Annotation
more info
 
glucokinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
glucose binding IEA
Inferred from Electronic Annotation
more info
 
hexokinase activity IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
mannokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 
cellular glucose homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
cellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 
glucose import IGI
Inferred from Genetic Interaction
more info
PubMed 
glucose metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycolytic process IDA
Inferred from Direct Assay
more info
PubMed 
glycolytic process IEA
Inferred from Electronic Annotation
more info
 
mannose metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Names
glucokinase
NP_009890.1
  • Glucokinase; catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources; GLK1 has a paralog, EMI2, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    50838..52340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178685.1NP_009890.1  TPA: glucokinase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009890.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17709
    Conserved Domains (3) summary
    COG5026
    Location:1500
    COG5026; Hexokinase [Carbohydrate transport and metabolism]
    pfam00349
    Location:17228
    Hexokinase_1; Hexokinase
    pfam03727
    Location:245499
    Hexokinase_2; Hexokinase
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