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APA1 bifunctional AP-4-A phosphorylase/ADP sulfurylase [ Saccharomyces cerevisiae S288C ]

Gene ID: 850307, updated on 8-Apr-2018
Gene symbol
APA1
Gene description
bifunctional AP-4-A phosphorylase/ADP sulfurylase
Primary source
SGD:S000000555
Locus tag
YCL050C
Gene type
protein coding
RNA name
bifunctional AP-4-A phosphorylase/ADP sulfurylase
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
DTP1
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (37836..38801, complement)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene Pbn1p Neighboring gene Lre1p Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP adenylyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
bis(5'-nucleosyl)-tetraphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
bis(5'-nucleosyl)-tetraphosphatase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
bis(5'-nucleosyl)-tetraphosphatase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
sulfate adenylyltransferase (ADP) activity IDA
Inferred from Direct Assay
more info
PubMed 
sulfate adenylyltransferase (ADP) activity IEA
Inferred from Electronic Annotation
more info
 
sulfate adenylyltransferase (ADP) activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
nucleoside catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
nucleoside catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
nucleoside catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleotide biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm HDA PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus HDA PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
bifunctional AP-4-A phosphorylase/ADP sulfurylase
NP_009880.2
  • AP4A phosphorylase; bifunctional diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase and ADP sulfurylase involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; catalyzes phosphorolysis of dinucleoside oligophosphates, cleaving substrates' alpha/beta-anhydride bond and introducing Pi into the beta-position of the corresponding NDP formed; protein abundance increases under DNA replication stress; APA1 has a paralog, APA2, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    37836..38801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178695.1NP_009880.2  TPA: bifunctional AP-4-A phosphorylase/ADP sulfurylase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009880.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P16550
    Conserved Domains (1) summary
    COG4360
    Location:2310
    APA2; ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) [Nucleotide transport and metabolism]
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