U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SMIM3 small integral membrane protein 3 [ Homo sapiens (human) ]

Gene ID: 85027, updated on 22-Sep-2022

Summary

Official Symbol
SMIM3provided by HGNC
Official Full Name
small integral membrane protein 3provided by HGNC
Primary source
HGNC:HGNC:30248
See related
Ensembl:ENSG00000256235 MIM:608324; AllianceGenome:HGNC:30248
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NID67; MST150; C5orf62
Summary
Enables identical protein binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in fat (RPKM 64.3), bone marrow (RPKM 21.5) and 18 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SMIM3 in Genome Data Viewer
Location:
5q33.1
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (150778757..150796734)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (151315272..151333249)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (150158319..150176296)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 22 Neighboring gene dynactin subunit 4 Neighboring gene uncharacterized LOC124901110 Neighboring gene Sharpr-MPRA regulatory region 7532 Neighboring gene uncharacterized LOC124901113 Neighboring gene immunity related GTPase M

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC117221, MGC126887, MGC126889

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small integral membrane protein 3
Names
NGF-induced differentiation clone 67 protein
Uncharacterized protein C5orf62
small membrane protein NID67

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032947.5NP_116565.3  small integral membrane protein 3

    See identical proteins and their annotated locations for NP_116565.3

    Status: VALIDATED

    Source sequence(s)
    BC106040
    Consensus CDS
    CCDS47312.2
    UniProtKB/Swiss-Prot
    Q6ZUV4, Q9BZL3
    Related
    ENSP00000436897.1, ENST00000526627.2
    Conserved Domains (1) summary
    pfam17307
    Location:160
    Smim3; Small integral membrane protein 3

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    150778757..150796734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    151315272..151333249
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)