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TMEM60 transmembrane protein 60 [ Homo sapiens (human) ]

Gene ID: 85025, updated on 22-Sep-2022

Summary

Official Symbol
TMEM60provided by HGNC
Official Full Name
transmembrane protein 60provided by HGNC
Primary source
HGNC:HGNC:21754
See related
Ensembl:ENSG00000135211 AllianceGenome:HGNC:21754
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DC32; C7orf35
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis (RPKM 13.9), thyroid (RPKM 12.6) and 25 other tissues See more
Orthologs
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Genomic context

See TMEM60 in Genome Data Viewer
Location:
7q11.23
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (77793728..77798434, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (79045656..79050361, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (77423045..77427751, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375363 Neighboring gene Alu-mediated CDKN1A/p21 transcriptional regulator Neighboring gene round spermatid basic protein 1 like Neighboring gene putative homeodomain transcription factor 2 Neighboring gene uncharacterized LOC124901682 Neighboring gene DDX3 interacting lncRNA 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC74482

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032936.4NP_116325.1  transmembrane protein 60

    See identical proteins and their annotated locations for NP_116325.1

    Status: VALIDATED

    Source sequence(s)
    AC004955, AF260336, BX117806
    Consensus CDS
    CCDS5593.1
    UniProtKB/Swiss-Prot
    Q86UM0, Q9H2L4
    Related
    ENSP00000257663.3, ENST00000257663.4
    Conserved Domains (1) summary
    pfam10269
    Location:25118
    Tmemb_185A; Transmembrane Fragile-X-F protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    77793728..77798434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    79045656..79050361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)