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UBL7 ubiquitin like 7 [ Homo sapiens (human) ]

Gene ID: 84993, updated on 5-Jan-2020

Summary

Official Symbol
UBL7provided by HGNC
Official Full Name
ubiquitin like 7provided by HGNC
Primary source
HGNC:HGNC:28221
See related
Ensembl:ENSG00000138629 MIM:609748
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TCBA1; BMSC-UbP
Expression
Ubiquitous expression in testis (RPKM 17.2), brain (RPKM 14.5) and 25 other tissues See more
Orthologs

Genomic context

See UBL7 in Genome Data Viewer
Location:
15q24.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (74445977..74461829, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (74738318..74753545, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2255 Neighboring gene CRISPRi-validated cis-regulatory element chr15.2230 Neighboring gene microRNA 6881 Neighboring gene semaphorin 7A (John Milton Hagen blood group) Neighboring gene UBL7 antisense RNA 1 (head to head) Neighboring gene uncharacterized LOC102723714 Neighboring gene AT-rich interaction domain 3B Neighboring gene VISTA enhancer hs1510

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC14421

Gene Ontology Provided by GOA

Function Evidence Code Pubs
polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ubiquitin-like protein 7
Names
ubiquitin-like 7 (bone marrow stromal cell-derived)
ubiquitin-like protein SB132

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286739.1NP_001273668.1  ubiquitin-like protein 7 isoform a

    See identical proteins and their annotated locations for NP_001273668.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same isoform (a).
    Source sequence(s)
    BC030055, BG704085, HY135530
    Consensus CDS
    CCDS10263.1
    UniProtKB/Swiss-Prot
    Q96S82
    Related
    ENSP00000457708.1, ENST00000565335.5
    Conserved Domains (2) summary
    cd01815
    Location:1892
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    cd14326
    Location:346375
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
  2. NM_001286740.1NP_001273669.1  ubiquitin-like protein 7 isoform a

    See identical proteins and their annotated locations for NP_001273669.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same isoform (a).
    Source sequence(s)
    BC007913, HY135530
    Consensus CDS
    CCDS10263.1
    UniProtKB/Swiss-Prot
    Q96S82
    Conserved Domains (2) summary
    cd01815
    Location:1892
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    cd14326
    Location:346375
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
  3. NM_001286741.1NP_001273670.1  ubiquitin-like protein 7 isoform b

    See identical proteins and their annotated locations for NP_001273670.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a longer N-terminus, compared to isoform a. Both variants 5 and 6 encode the same isoform.
    Source sequence(s)
    BC007913, BP192909, HY135530
    UniProtKB/Swiss-Prot
    Q96S82
    UniProtKB/TrEMBL
    D3DW56
    Conserved Domains (3) summary
    cd01815
    Location:58132
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    smart00213
    Location:79130
    UBQ; Ubiquitin homologues
    cd14326
    Location:386415
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
  4. NM_001286742.1NP_001273671.1  ubiquitin-like protein 7 isoform b

    See identical proteins and their annotated locations for NP_001273671.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a longer N-terminus, compared to isoform a. Both variants 5 and 6 encode the same isoform.
    Source sequence(s)
    BC030055, BC033919, BP192909, HY135530
    UniProtKB/Swiss-Prot
    Q96S82
    UniProtKB/TrEMBL
    D3DW56
    Conserved Domains (3) summary
    cd01815
    Location:58132
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    smart00213
    Location:79130
    UBQ; Ubiquitin homologues
    cd14326
    Location:386415
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
  5. NM_032907.5NP_116296.1  ubiquitin-like protein 7 isoform a

    See identical proteins and their annotated locations for NP_116296.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the shorter isoform (a). Variants 1-4 encode the same isoform.
    Source sequence(s)
    BC007913, BP192909
    Consensus CDS
    CCDS10263.1
    UniProtKB/Swiss-Prot
    Q96S82
    Related
    ENSP00000378518.2, ENST00000395081.7
    Conserved Domains (2) summary
    cd01815
    Location:1892
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    cd14326
    Location:346375
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
  6. NM_201265.1NP_957717.1  ubiquitin-like protein 7 isoform a

    See identical proteins and their annotated locations for NP_957717.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same isoform (a).
    Source sequence(s)
    BC007913, BI552240
    Consensus CDS
    CCDS10263.1
    UniProtKB/Swiss-Prot
    Q96S82
    Related
    ENSP00000354883.4, ENST00000361351.8
    Conserved Domains (2) summary
    cd01815
    Location:1892
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    cd14326
    Location:346375
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    74445977..74461829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450093.1XP_024305861.1  ubiquitin-like protein 7 isoform X1

    Conserved Domains (2) summary
    cd01815
    Location:100174
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    cd14326
    Location:428457
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
  2. XM_011522124.2XP_011520426.1  ubiquitin-like protein 7 isoform X2

    See identical proteins and their annotated locations for XP_011520426.1

    UniProtKB/TrEMBL
    D3DW56
    Conserved Domains (3) summary
    cd01815
    Location:58132
    BMSC_UbP_N; Ubiquitin-like domain of BMSC-UbP
    smart00213
    Location:79130
    UBQ; Ubiquitin homologues
    cd14326
    Location:386415
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_021160016.1 Reference GRCh38.p13 PATCHES

    Range
    275246..290457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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