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LSM10 LSM10, U7 small nuclear RNA associated [ Homo sapiens (human) ]

Gene ID: 84967, updated on 1-Jun-2020

Summary

Official Symbol
LSM10provided by HGNC
Official Full Name
LSM10, U7 small nuclear RNA associatedprovided by HGNC
Primary source
HGNC:HGNC:17562
See related
Ensembl:ENSG00000181817 MIM:617909
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MST074; MSTP074
Expression
Ubiquitous expression in lymph node (RPKM 20.1), spleen (RPKM 17.7) and 25 other tissues See more
Orthologs

Genomic context

See LSM10 in Genome Data Viewer
Location:
1p34.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (36393436..36397908, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (36859031..36863493, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene SH3 domain containing 21 Neighboring gene eva-1 homolog B Neighboring gene serine/threonine kinase 40 Neighboring gene Sharpr-MPRA regulatory region 4421 Neighboring gene RNA, U4 small nuclear 27, pseudogene Neighboring gene small nucleolar RNA, H/ACA box 63C Neighboring gene organic solute carrier partner 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: STK40

Homology

Clone Names

  • MGC15749

Gene Ontology Provided by GOA

Function Evidence Code Pubs
U7 snRNA binding IPI
Inferred from Physical Interaction
more info
PubMed 
histone pre-mRNA DCP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
histone mRNA metabolic process TAS
Traceable Author Statement
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
positive regulation of G1/S transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
termination of RNA polymerase II transcription TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
Cajal body IDA
Inferred from Direct Assay
more info
PubMed 
U7 snRNP IDA
Inferred from Direct Assay
more info
PubMed 
nuclear body IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
U7 snRNA-associated Sm-like protein LSm10
Names
U7 snRNP-specific Sm-like protein LSM10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032881.3NP_116270.1  U7 snRNA-associated Sm-like protein LSm10

    See identical proteins and their annotated locations for NP_116270.1

    Status: VALIDATED

    Source sequence(s)
    AC119675, AI150247, BC007623
    Consensus CDS
    CCDS408.1
    UniProtKB/Swiss-Prot
    Q969L4
    Related
    ENSP00000319341.2, ENST00000315732.3
    Conserved Domains (1) summary
    cd01733
    Location:885
    LSm10; Like-Sm protein 10

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    36393436..36397908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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