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NUDCD1 NudC domain containing 1 [ Homo sapiens (human) ]

Gene ID: 84955, updated on 21-Dec-2019

Summary

Official Symbol
NUDCD1provided by HGNC
Official Full Name
NudC domain containing 1provided by HGNC
Primary source
HGNC:HGNC:24306
See related
Ensembl:ENSG00000120526 MIM:606109
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CML66; OVA66
Expression
Ubiquitous expression in testis (RPKM 6.8), placenta (RPKM 5.8) and 25 other tissues See more
Orthologs

Genomic context

See NUDCD1 in Genome Data Viewer
Location:
8q23.1
Exon count:
12
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (109240919..109334087, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (110253148..110346486, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984017 Neighboring gene thyrotropin releasing hormone receptor Neighboring gene ENY2 transcription and export complex 2 subunit Neighboring gene PKHD1 like 1 Neighboring gene suppressor of cytokine signaling 5 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14991

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
immune system process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
nudC domain-containing protein 1
Names
chronic myelogenous leukemia tumor antigen 66
tumor antigen CML66
NP_001121683.1
NP_116258.2
XP_016869399.1
XP_016869400.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128211.1NP_001121683.1  nudC domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001121683.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' CDS, compared to variant 1, resulting in a protein (isoform 2) with a shorter, distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC021237, AK307663, BC043406
    Consensus CDS
    CCDS47910.1
    UniProtKB/Swiss-Prot
    Q96RS6
    Related
    ENSP00000410707.2, ENST00000427660.6
    Conserved Domains (1) summary
    cd06493
    Location:249332
    p23_NUDCD1_like; p23_NUDCD1: p23-like NUD (nuclear distribution) C-like domain found in human NUD (nuclear distribution) C domain-containing protein 1, NUDCD1 (also known as CML66), and similar proteins. NUDCD1/CML66 is a broadly immunogenic tumor associated antigen, ...
  2. NM_032869.4NP_116258.2  nudC domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_116258.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC021237, AF283301, AK307663, BC043406
    Consensus CDS
    CCDS6312.1
    UniProtKB/Swiss-Prot
    Q96RS6
    Related
    ENSP00000239690.4, ENST00000239690.9
    Conserved Domains (1) summary
    cd06493
    Location:278361
    p23_NUDCD1_like; p23_NUDCD1: p23-like NUD (nuclear distribution) C-like domain found in human NUD (nuclear distribution) C domain-containing protein 1, NUDCD1 (also known as CML66), and similar proteins. NUDCD1/CML66 is a broadly immunogenic tumor associated antigen, ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    109240919..109334087 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017013910.2XP_016869399.1  nudC domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q96RS6
    Conserved Domains (1) summary
    cd06493
    Location:191274
    p23_NUDCD1_like; p23_NUDCD1: p23-like NUD (nuclear distribution) C-like domain found in human NUD (nuclear distribution) C domain-containing protein 1, NUDCD1 (also known as CML66), and similar proteins. NUDCD1/CML66 is a broadly immunogenic tumor associated antigen, ...
  2. XM_017013911.1XP_016869400.1  nudC domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q96RS6
    Conserved Domains (1) summary
    cd06493
    Location:191274
    p23_NUDCD1_like; p23_NUDCD1: p23-like NUD (nuclear distribution) C-like domain found in human NUD (nuclear distribution) C domain-containing protein 1, NUDCD1 (also known as CML66), and similar proteins. NUDCD1/CML66 is a broadly immunogenic tumor associated antigen, ...
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