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TIGD5 tigger transposable element derived 5 [ Homo sapiens (human) ]

Gene ID: 84948, updated on 4-Jun-2020

Summary

Official Symbol
TIGD5provided by HGNC
Official Full Name
tigger transposable element derived 5provided by HGNC
Primary source
HGNC:HGNC:18336
See related
Ensembl:ENSG00000179886
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See TIGD5 in Genome Data Viewer
Location:
8q24.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (143597831..143603224)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (144680074..144682485)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene nicotinate phosphoribosyltransferase Neighboring gene eukaryotic translation elongation factor 1 delta Neighboring gene pyrroline-5-carboxylate reductase 3 Neighboring gene GDP-L-fucose synthase Neighboring gene uncharacterized LOC105375798

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14926, MGC44883

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tigger transposable element-derived protein 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032862.5NP_116251.4  tigger transposable element-derived protein 5

    See identical proteins and their annotated locations for NP_116251.4

    Status: VALIDATED

    Source sequence(s)
    AC067930
    Consensus CDS
    CCDS6406.2
    UniProtKB/Swiss-Prot
    Q53EQ6
    Related
    ENSP00000421489.2, ENST00000504548.4
    Conserved Domains (3) summary
    pfam03221
    Location:122182
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:53102
    HTH; Helix-turn-helix domains
    cl21549
    Location:273477
    rve; Integrase core domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    143597831..143603224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187571.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    87871..93264
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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