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MEDAG mesenteric estrogen dependent adipogenesis [ Homo sapiens (human) ]

Gene ID: 84935, updated on 2-Nov-2024

Summary

Official Symbol
MEDAGprovided by HGNC
Official Full Name
mesenteric estrogen dependent adipogenesisprovided by HGNC
Primary source
HGNC:HGNC:25926
See related
Ensembl:ENSG00000102802 AllianceGenome:HGNC:25926
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AWMS3; MEDA4; MEDA-4; hAWMS3; C13orf33
Summary
Predicted to be involved in positive regulation of fat cell differentiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in urinary bladder (RPKM 9.4), appendix (RPKM 6.9) and 19 other tissues See more
Orthologs
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Genomic context

See MEDAG in Genome Data Viewer
Location:
13q12.3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (30906271..30925572)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (30128196..30147488)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (31480408..31499709)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:31379396-31379896 Neighboring gene long intergenic non-protein coding RNA 398 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr13:31398576-31399105 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr13:31401421-31402065 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7545 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7546 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:31436564-31437514 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:31437515-31438463 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:31445187-31445996 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:31445997-31446806 Neighboring gene NANOG hESC enhancer GRCh37_chr13:31459446-31460017 Neighboring gene long intergenic non-protein coding RNA 545 Neighboring gene TEX26 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:31481009-31481510 Neighboring gene testis expressed 26 Neighboring gene uncharacterized LOC105370145 Neighboring gene NANOG hESC enhancer GRCh37_chr13:31557478-31558053 Neighboring gene long intergenic non-protein coding RNA 1066

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ14834, MGC126673, MGC126675

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of fat cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
mesenteric estrogen-dependent adipogenesis protein
Names
activated in W/Wv mouse stomach 3 homolog
mesenteric estrogen-dependent adipose 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032849.4NP_116238.3  mesenteric estrogen-dependent adipogenesis protein

    Status: VALIDATED

    Source sequence(s)
    AL353680
    Consensus CDS
    CCDS9338.1
    UniProtKB/Swiss-Prot
    Q5VYS4, Q8IXF1, Q96K26, Q96NC8
    Related
    ENSP00000369849.4, ENST00000380482.9

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    30906271..30925572
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017020801.2XP_016876290.1  mesenteric estrogen-dependent adipogenesis protein isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    30128196..30147488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054375073.1XP_054231048.1  mesenteric estrogen-dependent adipogenesis protein isoform X1