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RITA1 RBPJ interacting and tubulin associated 1 [ Homo sapiens (human) ]

Gene ID: 84934, updated on 13-Mar-2020

Summary

Official Symbol
RITA1provided by HGNC
Official Full Name
RBPJ interacting and tubulin associated 1provided by HGNC
Primary source
HGNC:HGNC:25925
See related
Ensembl:ENSG00000139405
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RITA; C12orf52
Expression
Ubiquitous expression in kidney (RPKM 8.8), liver (RPKM 6.7) and 25 other tissues See more
Orthologs

Genomic context

See RITA1 in Genome Data Viewer
Location:
12q24.13
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (113185526..113192368)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (113623342..113630169)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene deltex E3 ubiquitin ligase 1 Neighboring gene RAS protein activator like 1 Neighboring gene cilia and flagella associated protein 73 Neighboring gene microRNA 7106 Neighboring gene DEAD-box helicase 54 Neighboring gene IQ motif containing D Neighboring gene two pore segment channel 1 Neighboring gene microRNA 6762

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14827

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tubulin binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of Notch signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription by RNA polymerase II TAS
Traceable Author Statement
more info
PubMed 
neurogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
nuclear export IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear export IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
RBPJ-interacting and tubulin-associated protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286215.1NP_001273144.1  RBPJ-interacting and tubulin-associated protein 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' region and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AA594422, AK027733, BP212183, BX366456, DA207985
    Consensus CDS
    CCDS66473.1
    UniProtKB/Swiss-Prot
    Q96K30
    Related
    ENSP00000448680.1, ENST00000552495.1
    Conserved Domains (1) summary
    pfam17066
    Location:27293
    RITA; RBPJ-interacting and tubulin associated protein
  2. NM_032848.3NP_116237.1  RBPJ-interacting and tubulin-associated protein 1 isoform 1

    See identical proteins and their annotated locations for NP_116237.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
    Source sequence(s)
    AA594422, AK027733, DA207985
    Consensus CDS
    CCDS9166.1
    UniProtKB/Swiss-Prot
    Q96K30
    UniProtKB/TrEMBL
    A0A024RBL1
    Related
    ENSP00000449841.1, ENST00000548278.2
    Conserved Domains (1) summary
    pfam17066
    Location:3269
    RITA; RBPJ-interacting and tubulin associated protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    113185526..113192368
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005253972.3XP_005254029.1  RBPJ-interacting and tubulin-associated protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005254029.1

    UniProtKB/Swiss-Prot
    Q96K30
    UniProtKB/TrEMBL
    A0A024RBL1
    Related
    ENSP00000448289.1, ENST00000549621.5
    Conserved Domains (1) summary
    pfam17066
    Location:3269
    RITA; RBPJ-interacting and tubulin associated protein
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