Format

Send to:

Choose Destination

PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 [ Homo sapiens (human) ]

Gene ID: 84795, updated on 12-Aug-2018
Official Symbol
PYROXD2provided by HGNC
Official Full Name
pyridine nucleotide-disulphide oxidoreductase domain 2provided by HGNC
Primary source
HGNC:HGNC:23517
See related
Ensembl:ENSG00000119943 MIM:617889; Vega:OTTHUMG00000018877
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
YUEF; FP3420; C10orf33
Expression
Ubiquitous expression in prostate (RPKM 2.4), ovary (RPKM 1.9) and 25 other tissues See more
Orthologs
See PYROXD2 in Genome Data Viewer
Location:
10q24.2
Exon count:
23
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 10 NC_000010.11 (98383565..98415221, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (100143322..100174978, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene lysyl oxidase like 4 Neighboring gene uncharacterized LOC105378449 Neighboring gene microRNA 1287 Neighboring gene HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 Neighboring gene microRNA 4685 Neighboring gene uncharacterized LOC101927278

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

NHGRI GWAS Catalog

Description
A genome-wide assessment of variability in human serum metabolism.
NHGRI GWA Catalog
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.
NHGRI GWA Catalog
An atlas of genetic influences on human blood metabolites.
NHGRI GWA Catalog
Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
NHGRI GWA Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ12197, FLJ23849, MGC13047

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032709.2NP_116098.2  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2

    See identical proteins and their annotated locations for NP_116098.2

    Status: VALIDATED

    Source sequence(s)
    AK074429, AL139243, DC361966
    Consensus CDS
    CCDS7474.1
    UniProtKB/Swiss-Prot
    Q8N2H3
    Related
    ENSP00000359607.4, OTTHUMP00000020249, ENST00000370575.4, OTTHUMT00000049782
    Conserved Domains (2) summary
    COG1233
    Location:33580
    COG1233; Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism]
    cl21454
    Location:35578
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p12 Primary Assembly

    Range
    98383565..98415221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540293.2XP_011538595.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X1

    Conserved Domains (3) summary
    COG1233
    Location:77614
    COG1233; Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism]
    pfam13450
    Location:77118
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
    cl21454
    Location:312612
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  2. XM_017016838.1XP_016872327.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X4

    Conserved Domains (2) summary
    COG1233
    Location:32459
    COG1233; Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism]
    cl21454
    Location:157457
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  3. XM_017016839.2XP_016872328.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X4

    Conserved Domains (2) summary
    COG1233
    Location:32459
    COG1233; Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism]
    cl21454
    Location:157457
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  4. XM_017016840.1XP_016872329.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X4

    Conserved Domains (2) summary
    COG1233
    Location:32459
    COG1233; Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism]
    cl21454
    Location:157457
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  5. XM_017016841.1XP_016872330.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X4

    Conserved Domains (2) summary
    COG1233
    Location:32459
    COG1233; Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism]
    cl21454
    Location:157457
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  6. XM_011540301.2XP_011538603.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X5

    Conserved Domains (2) summary
    COG1233
    Location:1311
    COG1233; Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism]
    cl21454
    Location:9309
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  7. XM_017016835.1XP_016872324.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X2

  8. XM_017016837.1XP_016872326.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X3

  9. XM_017016836.1XP_016872325.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X3

RNA

  1. XR_001747236.1 RNA Sequence

  2. XR_001747237.1 RNA Sequence

  3. XR_001747233.1 RNA Sequence

  4. XR_001747238.1 RNA Sequence

  5. XR_001747239.1 RNA Sequence

  6. XR_001747235.1 RNA Sequence

  7. XR_001747234.1 RNA Sequence

  8. XR_001747240.1 RNA Sequence

Support Center