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FUT10 fucosyltransferase 10 [ Homo sapiens (human) ]

Gene ID: 84750, updated on 1-Jun-2020

Summary

Official Symbol
FUT10provided by HGNC
Official Full Name
fucosyltransferase 10provided by HGNC
Primary source
HGNC:HGNC:19234
See related
Ensembl:ENSG00000172728 MIM:616931
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FUCTX
Expression
Ubiquitous expression in ovary (RPKM 2.0), placenta (RPKM 1.5) and 25 other tissues See more
Orthologs

Genomic context

See FUT10 in Genome Data Viewer
Location:
8p12
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (33308102..33473146, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (33228057..33330664, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379362 Neighboring gene MT-ND2 pseudogene 32 Neighboring gene RAN pseudogene 9 Neighboring gene RNA, U6 small nuclear 528, pseudogene Neighboring gene RNA binding motif protein 4 pseudogene Neighboring gene small nucleolar RNA, C/D box 13 Neighboring gene MAK16 homolog Neighboring gene TELO2 interacting protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC11141

Gene Ontology Provided by GOA

Function Evidence Code Pubs
alpha-(1->3)-fucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
alpha-(1->3)-fucosyltransferase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
L-fucose catabolic process NAS
Non-traceable Author Statement
more info
PubMed 
cerebral cortex radially oriented cell migration IEA
Inferred from Electronic Annotation
more info
 
fertilization NAS
Non-traceable Author Statement
more info
PubMed 
fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hemopoiesis NAS
Non-traceable Author Statement
more info
PubMed 
nervous system development NAS
Non-traceable Author Statement
more info
PubMed 
neuronal stem cell population maintenance IEA
Inferred from Electronic Annotation
more info
 
protein folding NAS
Non-traceable Author Statement
more info
PubMed 
protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
protein glycosylation TAS
Traceable Author Statement
more info
PubMed 
protein targeting NAS
Non-traceable Author Statement
more info
PubMed 
wound healing NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
Golgi apparatus TAS
Traceable Author Statement
more info
PubMed 
Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
alpha-(1,3)-fucosyltransferase 10
Names
alpha (1,3) fucosyltransferase
alpha 1,3-fucosyl transferase
fuc-TX
fucT-X
fucosyltransferase X
galactoside 3-L-fucosyltransferase 10
NP_116053.3
XP_011542978.1
XP_011542979.1
XP_011542980.1
XP_011542981.1
XP_011542982.1
XP_011542983.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032664.3NP_116053.3  alpha-(1,3)-fucosyltransferase 10

    See identical proteins and their annotated locations for NP_116053.3

    Status: VALIDATED

    Source sequence(s)
    AJ582015, BC063462
    Consensus CDS
    CCDS6088.1
    UniProtKB/Swiss-Prot
    Q6P4F1
    Related
    ENSP00000332757.5, ENST00000327671.10
    Conserved Domains (2) summary
    pfam00852
    Location:219354
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:83177
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    33308102..33473146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011544676.3XP_011542978.1  alpha-(1,3)-fucosyltransferase 10 isoform X1

    Conserved Domains (2) summary
    pfam00852
    Location:261396
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:125219
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
  2. XM_011544678.2XP_011542980.1  alpha-(1,3)-fucosyltransferase 10 isoform X3

    Conserved Domains (2) summary
    pfam00852
    Location:191326
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:55149
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
  3. XM_011544677.3XP_011542979.1  alpha-(1,3)-fucosyltransferase 10 isoform X2

    Conserved Domains (2) summary
    pfam00852
    Location:219354
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:83177
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
  4. XM_011544681.3XP_011542983.1  alpha-(1,3)-fucosyltransferase 10 isoform X6

    Conserved Domains (2) summary
    pfam00852
    Location:261396
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:125219
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
  5. XM_011544679.3XP_011542981.1  alpha-(1,3)-fucosyltransferase 10 isoform X4

    Conserved Domains (2) summary
    pfam00852
    Location:261396
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:125219
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
  6. XM_011544680.3XP_011542982.1  alpha-(1,3)-fucosyltransferase 10 isoform X5

    Conserved Domains (2) summary
    pfam00852
    Location:261396
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:125219
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
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